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2) Therapeutic limitations and innovations: Current ferroptosis inhibitors (Fer-1, Lip-1, and DFO) suffer from poor aqueous solubility, short half-lives, and off-target effects (e.g., DFO-induced iron deficiency anemia)

Safety information on BPC-157 is primarily derived from animal studies

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Immunofluorescence cell imaging HeLa cells, untreated or BSO treated, were infected with wt or BSOr virus at a moi of 10 and were incubated for 4 hr at 37C, in the absence or presence of 0.4 mM BSO, respectively